Novel drug delivery system for oral lesions - A Literature Review

Abstract

Oral mucosal lesions, encompassing a diverse group of pathological conditions such as infections, Ulcers, inflammation, and neoplasia, present significant challenges in clinical management [1]. Traditional treatment approaches often involve systemic drug administration, which can lead to suboptimal drug concentrations at the target site and increase the risk of systemic side effects [2]. Consequently, there is a growing need for effective, localized drug delivery systems that can enhance therapeutic outcomes and minimize adverse effects [3].

Novel drug delivery systems (NDDS) offer promising avenues for the targeted treatment of oral mucosal lesions [4]. By utilizing innovative technologies and materials, these systems aim to improve drug bioavailability, prolong drug residence time at the lesion site, and enhance patient compliance [5]. This review explores the recent advancements in NDDS for oral mucosal lesions, highlighting their potential to revolutionize the management of these challenging conditions.