Investigation Of Phytochemical And Anti-Ulcer Activity Of Musa Sapientum (Banana)

Abstract

Through the use of in vitro models, the current research explored the possible antioxidant and antiulcer properties of extracts derived from the peel of Musa sapientum (banana). This was accomplished by employing the Soxhlet equipment to extract the peel powder in a sequential manner using solvents of varying polarity, including chloroform, ethyl acetate, methanol, and petroleum ether. Following phytochemical analysis, it was discovered that the substance in question contained flavonoids, glycosides, saponins, carbohydrates, and amino acids, all of which are chemicals that are recognised for their medicinal qualities. Assays for DPPH, hydrogen peroxide (H2O2), and nitric oxide (NO) scavenging were used to evaluate the antioxidant activity of the substance. The results showed that the substance possessed a significant radical neutralisation capacity that was comparable to that of typical antioxidants. The acid-neutralizing capacity (ANC) test demonstrated dose-dependent antacid activity (100-1500 mg), with higher dosages demonstrating effects that were comparable to those of standard antacids (magnesium/aluminum hydroxide). Based on these observations, it appears that peels manufactured from M. sapientum contain powerful bioactive chemicals that have the potential to protect against oxidative stress and stomach ulcers. Banana peels have been used for therapeutic purposes for centuries, and this study serves to substantiate those applications while also showing their potential as a natural and sustainable source of antioxidants and gastroprotective compounds. To determine the efficacy of the substance in vivo and to isolate the active ingredients, additional research is required.