Pharmacological and phytochemical screening Of Murraya koenigii oil base herbal cream

Abstract

This study explores the pharmacological and phytochemical properties of a topical herbal cream formulated with essential oil extracted from Murraya koenigii (curry leaves). Using hydrodistillation, essential oil was obtained from leaves collected in Dehradun, India, and subsequently incorporated into a cream base. Phytochemical screening revealed the presence of key bioactive compounds such as alkaloids, flavonoids, phenolics, and terpenoids. Gas Chromatography and Mass Spectrometry (GC-MS) analysis confirmed the presence of major components like sabinene, β-pinene, and limonene. The antifungal activity of the cream was evaluated against Candida albicans and Aspergillus brasiliensis using the agar well diffusion method, demonstrating notable zones of inhibition. These findings suggest that the formulated cream possesses significant antifungal properties and could serve as a promising natural alternative to conventional topical agents. Further clinical studies are recommended to confirm its therapeutic potential and safety.