The Effect of Occupation on Heavy Metals Concentrations and the Their Relationship to Blood Cancer Incidenence rates in Diwaniyah

Abstract

   "Heavy metal" describes a broad class of naturally occurring metallic elements with molecular weights and densities greater than those of water occur. These elements influence cells and livings beings in many manners; certain heavy metals possess important roles (such as iron, zinc, copper and manganese) and are harmful only in excessive amounts, while others are inherently highly hazardous (such as, arsenic, cadmium, lead and mercury). Consequently, all organisms and cells regulate metal homeostasis within physiological or sub-toxic and employ metal detoxification processes. Seventy-five samples from both gender were included in the present study with age range (15_70 years). 50 patients with blood diseases were selected from Teaching Al-Diwaniyah Hospital; and 25 participent apparently healthy control group. Heavy metals parameters measurement was performed on blood serum by use (Atomic absorption spectrophotometer), model Buck Scientific - 210VGP Atomic Absorption Spectrophotometer.The blood serum, were digestion to examine the heavy elements of the total study sample (treatment and control) As for occupation, employees constituted the highest percentage (36%), possibly reflecting the impact of work conditions on overall health. Studies have indicated that exposure to heavy metals can result in carcinogenic effects, disrupt various physiological processes, and increase cancer risk.Regarding diseases, the highest rate was among patients with Chronic Myeloid Leukaemia (CML) at 32%, emphasising the significance of this cancer type within the studied sample. Additionally, 60% of participants had no genetic diseases, which may suggest the influence of environmental or lifestyle factors the aim of study elevated the effect of occupation exposure on heavy metals concentrations among residents of diwaniyah Governorate and determine the relationship between this concentration and the incidence of Leukemia.