Analyzing Muscle Strength, Functional Performance and Metabolic Syndromes Associated in Women with Early Hysterectomy

Abstract

Background: Hysterectomy, particularly at an early age, has been associated with significant long-term health consequences. The removal of the uterus, often accompanied by ovarian dysfunction or oophorectomy, leads to hormonal imbalances, particularly oestrogen deficiency. Oestrogen plays a crucial role in maintaining bone density, muscle function, and metabolic syndromes. Understanding the implications of early hysterectomy on these physiological systems is essential for developing appropriate preventive and therapeutic interventions.

Objectives: This study aims to evaluate the correlation between early hysterectomy and its effects on muscle strength, functional performance and metabolic syndromes.

Materials and Methods:138 women of who underwent hysterectomy at the age between 35-45 years before natural menopause were taken. Outcome measures used were manual muscle testing, Musculoskeletal health questionnaire.

Results:Women who had hysterectomy at early age had a significant difference in core muscle strength, functional performance and metabolic syndromes than women without hysterectomy. Age and selected variables were highly correlated in the women with early age who had hysterectomy (p<0.0001).

Conclusion: Early hysterectomy is strongly correlated with adverse effects on muscle function and metabollic syndromes primarily due to oestrogen depletion. These findings emphasize the need for early intervention strategies, including hormonal management, physical rehabilitation, and cardiovascular risk monitoring, to mitigate long-term complications in affected individuals. Further research is warranted to explore targeted therapies for improving post-hysterectomy outcomes.