Correlation with Menstrual Irregularities and Hypothyroidism after Pregnancy

Abstract

Background: Menstrual irregularity is a gynecological problem with hypothyroidism after pregnancy and a cause of anxiety to the females and those lose to them. Disturbance of the hypothalamic-pituitary-ovarian (HPO) axis pathway results in an irregular menstrual cycle, Oligomenorrhea, Dysmenorrhea, are the cconditions related to irregular menstruation.

Objective: This study aimed to assessment of the menstrual irregularity with hypothyroidism after pregnancy in selected general hospital, Bhopal district, Madhya Pradesh, India in during December 2024 to May 2025.

Methods: A cross-sectional study was conducted at general hospital. Data was collected using questionnaires in 100 eligible females having thyroid problem, out of these 50 were hypothyroidism we assess only hypothyroidism as case study other 50   patient’s samples as control either hyperthyroidism or normal thyroid profile but problem having menstrual cycle attending outpatient and inpatient department of obstetrics and gynecological and pathology lab at general hospital. Weight and height were measured and Body Mass Index (BMI) was calculated and thyroid profile testing (T3, T4, and TSH) was done after data collection.

Results: The result showed that the selected demographic variables such as Age, Residence and Gynaecologic problems in our study, mean value of thyroid profile in total patients were T3- 0.85±0.37, T4 -6.41±3.1 and TSH-32.02±2.26. Results depict the mean value of T3, T4, TSH hormones level. These results showed that there were significant low levels of both of T3 and T4 levels0.85±0.37, T4 -6.41±3.1 whereas TSH levels 32.02±2.26 higher than its normal values: Total T3: 80–220 ng/dL, Total T4: 5.0–12.0 µg/dL, TSH: 0.4–4.0 mIU/L (optimal range: 0.45–2.5 mIU/L for adults) whereas menstrual irregularities like 10 polymenorrhagia, 8 hypomenorrhea/oligomenorrhea, 10 polymenorrhagia and 7 amenorrhea respectively and mostly cases was 25 menorrhagia. The findings revealed that there was a significant association of menstruation irregularities with menorrhagia.

Conclusion: The connection between hypothyroidism and menstrual irregularities is essential for managing your health effectively. Thyroid dysfunction can significantly impact menstrual cycles, the results highlight the necessity of routine thyroid function screenings for women you can take control of your health and improve your quality of life, facilitating precise diagnosis and suitable treatment.