Investigation Of Rhinacanthus Nasutus For Cns Activity Using Albino Mice

Abstract

The aim of this present study is to investigate central nervous system activity of the ethyl acetate and ethanol extract of leaves of Rhinacanthus Nasutus in dose variation. The work reached the acute toxicity studies plant and its action on the central nervous system, because no data in the literature have been found of pharmacological activity of this plant in the central nervous system. The leaves were extracted with ethyl acetate and ethanol and investigated for its central nervous system activity of Albino mice in Rota-rod and Actophotometer at the dose level of 200 and 400 mg/kg. The extract exhibited significant central nervous system activity. This study established central nervous system activity in plant leaves.