Environmentally Shrewdly Innoxious Phyto-Chemical Route Synthesis of Silver Nanoparticles and Their Ingress on Multi-Drug Resistance Bacteria

Abstract

Nanoparticles synthesis by means of plant extracts is one of the greatest unpretentious, convenient, environmentally friendly, and economically beneficial approaches that alleviate the engrossment of noxious chemicals. Hence, in recent years, several eco-friendly processes for the rapid synthesis of silver nanoparticles have been reported using aqueous extracts of plant parts such as the leaf, bark, roots, etc. This review summarizes and elaborates the new findings in this research domain of the green synthesis of silver nanoparticles (AgNPs) using different plant extracts and their potential applications as antimicrobial agents. While highlighting the recently used different plants for the synthesis of highly efficient antimicrobial green AgNPs, we aim to provide a systematic in-depth discussion on the possible influence of the phytochemicals and their concentrations in the plants extracts, extraction solvent, and extraction temperature, as well as reaction temperature, pH, reaction time, and concentration of precursor on the size, shape and stability of the produced AgNPs. Exhaustive details of the plausible mechanism of the interaction of AgNPs with the cell wall of microbes, leading to cell death, and high antimicrobial activities have also been elaborated.   The leaves of Ionidium Suffruticosum  were collected, shadow dried, crushed and further nano size powdered by mixer mill and then liquidity extracted through maceration process. The prepared leaf extract used to synthesis the silver nanoparticles(AgNPs) and characterized by using UV, XRD, SEM, and DLS as well as subjected to evaluate the presence of  phytochemicals and   antibacterial activity against selected multi drug resistance bacterial strains.