Comparative Evaluation of Healing Following Gingival Laser Depigmentation Procedure with and Without Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Split-Mouth Clinical Trial
DOI:
https://doi.org/10.64252/hkjksa75Keywords:
Laser depigmentation, Injectable platelet-rich fibrin, Gingival pigmentation, Healing index, Split-mouth trialAbstract
AIM - To compare healing following gingival laser depigmentation with and without the application of injectable Platelet-Rich Fibrin (i-PRF).
MATERIALS AND METHODS - A randomized controlled split-mouth clinical trial was conducted on systemically healthy patients with gingival hyperpigmentation. Laser depigmentation was performed using a diode laser (980 nm). On the test side, i-PRF was prepared from venous blood and injected into the depigmented area; on the control side, no i-PRF was used. Healing was assessed using Landry’s Healing Index, epithelization with 5% hydrogen peroxide, and recurrence with Dummett Gupta Oral Pigmentation Index.
RESULTS - Sites treated with i-PRF showed better healing scores, faster epithelization, and reduced recurrence of pigmentation compared to control sites.
CONCLUSION - Adjunctive use of injectable PRF after gingival laser depigmentation enhances wound healing and reduces recurrence.




