Comparative Evaluation of Healing Following Gingival Laser Depigmentation Procedure with and Without Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Split-Mouth Clinical Trial

Authors

  • Dr. Chanchal Bherwani, Dr. Arvind Shetty, Dr. Suyog Dharmadhikari, Dr. Tasmiya Khan, Dr. Yashashree Chande, Dr. Ratnakar Saswadkar, Dr. Muzzammil Mukadam Author

DOI:

https://doi.org/10.64252/hkjksa75

Keywords:

Laser depigmentation, Injectable platelet-rich fibrin, Gingival pigmentation, Healing index, Split-mouth trial

Abstract

AIM - To compare healing following gingival laser depigmentation with and without the application of injectable Platelet-Rich Fibrin (i-PRF).

MATERIALS AND METHODS - A randomized controlled split-mouth clinical trial was conducted on systemically healthy patients with gingival hyperpigmentation. Laser depigmentation was performed using a diode laser (980 nm). On the test side, i-PRF was prepared from venous blood and injected into the depigmented area; on the control side, no i-PRF was used. Healing was assessed using Landry’s Healing Index, epithelization with 5% hydrogen peroxide, and recurrence with Dummett Gupta Oral Pigmentation Index.

RESULTS - Sites treated with i-PRF showed better healing scores, faster epithelization, and reduced recurrence of pigmentation compared to control sites.

CONCLUSION - Adjunctive use of injectable PRF after gingival laser depigmentation enhances wound healing and reduces recurrence.

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Published

2025-09-01

Issue

Section

Articles

How to Cite

Comparative Evaluation of Healing Following Gingival Laser Depigmentation Procedure with and Without Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Split-Mouth Clinical Trial. (2025). International Journal of Environmental Sciences, 3054-3062. https://doi.org/10.64252/hkjksa75