Impact of Bovine Colostrum Nutraceuticals on Hematological Indices and Ratios in Elderly Patients with Type 2 Diabetes: A Single Blind Randomized Clinical Trial

Abstract

A group of metabolic diseases known as diabetes mellitus is characterized by hyperglycaemia brought on by deficiencies in either insulin secretion, insulin action, or both.

People who are of old age frequently use several modalities of nutraceutical supplements to improve their general health. To ascertain the impact of oral bovine colostrum (BC) nutraceutical intake on the blood cell components and hematological ratios in participants undergoing their disease. A randomized, placebo-controlled trial was conducted at Al-Karama Teaching Hospital, Wasit, Iraq, the trial commenced on August 20, 2024, and was completed on December 10, 2024. 62 Elderly Patients with Type 2 Diabetes were divided into two groups: Group I, which received a placebo, and Group II, which received an oral dose of 500 mg BC capsule per day for eight weeks.  At the beginning and completion of the study, the anthropometric and homological indicators were calculated. The anthropometric parameters in both groups did not significantly change. The number of granulocytes, mean corpuscular volume, mean platelet volume, and platelet large cell ratio all decreased in Group II individuals, while hemoglobin and mean corpuscular hemoglobin concentration increased. Compared to Group II, reciprocal changes in the granulocyte-to-lymphocyte and platelet-to-lymphocyte ratios were seen. We conclude that ovine colostrum is an advantageous nutritional supplement for athletes since it raises hematological ratios and indices.