Structure-Activity Relationship of Phytochemicals for Combating Covid-19 Brain Fog

Abstract

The pandemic SARS-COV-2 caused by a strain of acute respiratory syndrome of corona virus has killed millions of people worldwide. The direct impact on the health economy of affected countries. More than 219 countries have been severely affected by COVID-19. There are no specific small molecule inhibitors against this virus. Section various anti-inflammatory drugs such as antibiotics, anti-inflammatory drugs, antiviral drugs and antiviral drugs are also used in the treatment of covid-19. The full effect of this drug against covid-19 targets has not been tested. After receiving treatment, the virus can change its genetic materials, more strains formed causing the dangerous epidemic. Covid-19 types of delta plus and omicron kill brain cells and cause long-term COVID-19 memory. There are currently no synthetic drugs available to treat the memory loss due to long COVID-19 brain fog. Therefore, an attempt has been made to treat COVID-19 associated brain fog using natural components. The biochemical mechanism of action of these phytocomponents has been predicted using structure-based docking simulation.