Formulation Development And Evaluation Of Azelaic Acid Face Serum

Abstract

The aim of present study was to prepared a skin brightening face serum for better absorption. Face serum of azelaic acid was prepared by using xanthan gum and propylene  glycole by simple mixture method. The prepared face serum were evaluated for pH, drug content, viscosity and spreadability. In vitro drug relese study was carried by using diffusion cell with dialysis membrane. The drug content and pH of the formulation were found to be satisfactory.

The pH of  the formulation found to be in the range of pH 4.99 to 5.45.The viscosity and spredability of the formulations were found to be satisfactory. Formulation F3 containing 0.03% Xanthan gum and 1.1% Propylene glycol showed highest drug release of  89.99 % . The developed formulations showed sustained release of drug up to 8 hrs. From in-vitro drug release studies.