Pharmacological Effects Of Artemisia Roxburghiana Leaves On Letrozole Induced PCOS In Female Wistar Rats

Abstract

Polycystic ovarian affliction (PCOS), also dubbed as PCOD, is a shape where a woman's hormones are not balanced. It might diminish the chances of conception and result in issues with their periods. If left untreated, it can eventually result in major health issues like diabetes and heart disease. This study evaluates pharmacological effects of Artemisia roxburghiana leaves on letrozole induced PCOS in female Wistar rats.  The experimental technique involves generating of letrozole induced PCOS followed by therapy with ethanolic extract of Artemisia roxburghiana.  The research focused on analysing the physical parameters, LH, FSH and testosterone level in blood and histology of ovaries.  Results demonstrated that ethanolic extract of Artemisia roxburghiana dramatically improved body weight, improved LH FSH level, regulated testosterone level disturbed by letrozole induced PCOS.  The findings showed the potential effect of ethanolic extract of Artemisia roxburghiana in the treatment of PCOS, giving a possible alternative to current pharmaceutical treatments.