Formulation and Evaluation of Poly Herbal Tablet of Some Selected Herbs with Potent Anti Inflammatory Activity

Abstract

The main objective of the present study was to develop a polyherbal tablet and to evaluate anti-inflammatory activity. Based on the available traditional and scientific,literature, herbs that possess anti-inflammatory activity were selected. The successive extraction of the leaves of Anacyclus pyrethrum, Foeniculum vulgare, and Valeriana jatamansi using petroleum ether, chloroform, ethanol, and water as solvents yielded extracts with varying quantities and characteristics, reflecting the polarity and solubility of phytoconstituents present in each plant The in vitro anti-inflammatory activity of petroleum ether, chloroform, ethanolic, and aqueous extracts of leaves of Anacyclus pyrethrum, Foeniculum vulgare, and Valeriana jatamansi was evaluated using the Human Red Blood Cell (HRBC) membrane stabilization method using Diclofenac sodium as standard to study the anti-inflammatory activity. Herbal tablets were prepared by direct compression method. Tablet formulations with varying concentration of the active fractions of various herbs were prepared and standardised.