Immunological Detection of Toxoplasma Gondii Among Patients Suffering Helicobacter Pylori Gastritis and Gastric Ulcer

Abstract

Simultaneous infection with H. pylori and T. gondii is common and occurs via the transmission of fecal matter to the mouth. Both infections are associated with gastritis and peptic ulcer disorders. Objectives: Both H. pylori infection and Toxoplasmosis symptoms are very common illnesses that are transmitted by the fecal-oral channel. The primary objective of this research was to investigate the link between these two diseases Materials: In order to conduct upper and lower bronchoscopy, as well as gastrointestinal endoscopy, the patients were transported to the gastroenterology clinic at Azadi Teaching Hospital as well as the private Kirkuk clinic in Kirkuk city. Both of these clinics are located in an educational institution. Methods: This particular research had been conducted during the months of November 2021 and April 2022. This patient's group consisted of 148 individuals in total. The ages of the patients ranged from 20 to 40 years. Stool antigen test and ELISA (IgM and IgG) for Toxoplasma species were performed on a subset of patients who were eligible for the study. The examination was performed according to non-invasive procedures. Result: In the current research, 78 patients (female) exhibited a positive result for H. pylori, which had been found by stool antigen test. Additionally, 31 patients (39.7%) showed positive results for T. gondii by utilizing ELISA technique since they had a positive result in H. pylori. Conclusion: When H. pylori was paired with toxoplasmosis, it resulted in the return of the latter, which in turn caused a more severe case of gastritis and a stomach ulcer.