Natural Herbal Formulations for the Management of Oral Submucous Fibrosis (OSMF): A Systematic Review

Abstract

Oral Submucous Fibrosis (OSMF) is a potentially malignant disorder that affects the oral mucosa, causing pain, restricted mouth opening, and difficulty in oral functions. Conventional treatments often come with significant side effects and limited efficacy. This review explores the potential of natural herbal formulations, including curcumin, Aloe vera, licorice, and Triphala, in managing OSMF. The effectiveness, safety, and cost-effectiveness of these herbs are evaluated based on clinical studies, with a focus on symptom relief, fibrosis reduction, and prevention of malignant transformation. The findings suggest that these herbal formulations may offer a safer, more affordable, and less invasive alternative to conventional therapies. However, further clinical trials with standardized dosages and larger sample sizes are needed to confirm their efficacy.