The Role and Relationship of Betatrophin with Exercise Among Obese Patients in Gym Centers in Mosul City

Abstract

Obesity is characterized by an increase in body fat and adipose tissue and is a cause of metabolic syndrome. therefore, the study contributed to studying the effect of exercise on the hormone betatrophin and its relationship to biochemical parameters related to obesity, the results showed that there was a significant increase in the level of betatrophin, which was (586.2±112.6pg/ml) compared to healthy individuals, which was (253.6±37.2pg/ml)pre- exercise, while its level was (436.3±95.5pg/ml) compared to the control group, which was (200.8±23.5pg/ml)post-exercise.also, a significant increase in the level of betatrophin was observed in females more than males, and its level increased with increasing age and BMI ,While the level of betatrophin decreased with increasing duration of exercise,the results showed that pre-exercise there was a significant increase in insulin resistance, glucose, HbA1c , urea, creatinine, cholesterol, triglycerides, LDL-C, VLDL, atherogenic index, peroxidase enzyme, and a decrease in their levels post exercise. while there was a significant decrease in insulin, HDL-C, ARE enzymes, catalase, uric acid pre-exercise and an increase in their levels post-exercise,the research aimed to study the effect of exercise and its duration on the level of betatrophin and some clinical parameters related to obesity, and to study the relationship of betatrophin to antibiotics and oxidative stress..