Prepration and Evaluation Of Polyherbal Suspension For Anti-Diabetic Activity
DOI:
https://doi.org/10.64252/ag455v73Keywords:
Antidiabetic Herbs, antidiabetic activity of Amla, Baheda, Jamun, Karela, Nut Tree, Smilex China.Abstract
In the present study the antihyperglycemic properties of the specially formulate polyherbal formulation in Streptozotocin induced diabetic rats was determined. Diabetes was induced in Albino rats by administration of streptozotocin. The formulation i.e Polyherbal suspension was administered to diabetes induced rats for a period of 45 days, which possess better effect. Additional biochemical parameters such as serum cholesterol, triglycerides, HDL-cholesterol, LDL cholesterol levels were also measured at the ending of study. After verify the antidiabetic property of Polyherbal suspension on blood glucose was observed the finest one, in order to justify it we have to check its oxidative parameter , and LPO, Which enzyme indicate its oxidative stress. In the present study poly herbal extracts of antidiabetic activity of Amla, Baheda, Jamun, Karela, Nut Tree, Smilex China are prepared and converted into suspension using organic solvents. Those polyherbal suspensions were evaluated. From the above outcome it is concluded that the formulation 200 mg/kg on blood glucose possesses significant antidiabetic effects in streptozotocin induced diabetic rats. By through analytical justification i.e chromatographic separation, HPLC techniques, Spectroscopic technique the responsible phytoconstituent for physicochemical property was more justified.