Pharmacological Activity Of Green Synthesized Silver Nanoparticles Of Argemone Mexicana As Antifungal Agent

Abstract

Antimicrobial resistance  development has grown to be a serious health issue. Therefore, the need to find better, more powerful tactics to combat Antimicrobial resistance remains ongoing. Silver nanoparticles (AgNPs) possess unique physico-chemical and excellent antifungal properties. AgNPs have been shown to have antifungal properties in numerous investigations. So, the budding potential of AgNPs as antifungal should be a positive indication to combat Antimicrobialresistance  . The green method of AgNP production using plant material has several advantages: freedom from toxic chemicals, cost effectiveness, simplicity, easy scalability, economic viability, and eco-friendliness. AgNPs have been synthesized using different parts of plants, including fruit, seed, bark, peel, root, and leaf. In order to successfully reduce the silver salt and stabilize/cap the nanoparticles, secondary metabolites present in plant extract, such as polyphenols, terpenoids, flavonoids, proteins, saponins, and vitamins, are required. In addition to their role in the efficient synthesis of AgNPs, synergistic interaction between the plant extract and AgNPs might result in a marked increase in the observed antifungal activity. Based on their phytochemical profile and antimicrobial activity A. maxicana  selected to synthesize AgNPs. Moreover, forming AgNPs using the plants may synergize between nanoparticles and plant extracts for antifungal activity.