The Gut Microbiome And Mental Health

Authors

  • Govindan Shakeela Author
  • Andamuthu Yamunadevi Author
  • Abikshyeet Panda Author
  • Neelamegam Preethi Author
  • Jeyakumari Paul Author
  • Thangadurai Maheswaran Author

DOI:

https://doi.org/10.64252/sv1s9s65

Keywords:

Diet, Gut microbiome, Gut microbiota, Mental health, Microbiota-gut-brain-axis, Prebiotics, Probiotics.

Abstract

A balanced gut microbiome is necessary to maintain good mental health.The inexplicable relationship between the gut microbiome and mental health has emerged as a notable area of scientific exploration. Recent research has established a competing bi-directional relationship between the gut microbiome and mental health outcomes.The gut-brain axis(GBA), a bi-directional communication pathway involving the gut microbiome,central nervous system and enteric nervous system,has emerged as a vital element in mental health disorders. GBA can monitor and combine gut activities, connecting emotional and cognitive centers.Communication within the GBA is facilitated by neurology, immunology and endocrinology.This review synthesizes current research on the relationship between gut microbiome and mental health conditions, including depression, anxiety and schizophrenia.This review highlights the key mechanisms of the gut -brain axis, the role of specific microbial species, the impact of diet and lifestyle, dysbiosis in several mental disorders and the therapeutic potential of targeting the microbiome. It also suggests novel avenues for understanding, diagnosing and medicating a wide range of psychiatric conditions. It identifies crucial research gaps, offering insights for advancing mental healthcare through innovative microbiome-informed approaches. This review concludes by illuminating the importance of continued research to further elucidate these complex interactions and translate findings into effective clinical interventions.

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Published

2025-07-17

Issue

Section

Articles

How to Cite

The Gut Microbiome And Mental Health. (2025). International Journal of Environmental Sciences, 814-823. https://doi.org/10.64252/sv1s9s65