“Comparative evaluation of chlorhexidine mouthwash with and without an anti-discoloration system - a randomized controlled trial"

Abstract

Objective: This research seeks to determine if a formulation combining chlorhexidine with an agent to counteract discoloration (ADS)lowers the risk of external tooth staining while maintaining clinical efficacy comparable to standard 0.2% chlorhexidine mouthwash. Secondary aim includes evaluating patient adherence to prescribed usage protocols and identifying and characterizing any adverse effects associated with either mouthwash.

Procedure: A trial conducted using a single-blind format and randomized group distribution was performed on 40 non-smoking patients who had been diagnosed with chronic gingivitis. Participants were assigned to use either a conventional mouthwash (control group; Bottle B) or a chlorhexidine-based mouthwash enhanced with an anti-discoloration system (ADS) (test group; Bottle A) over a 15-day period. A complete dental cleaning was conducted before the beginning of each treatment phase. Prior to the start of each intervention phase, a full dental prophylaxis was performed. Clinical evaluations were conducted using the indices assessing dental plaque (plaque index), gum health (gingival index), bleeding response during probing (bleeding on probing index) and the Modified Staining Index to assess both oral hygiene status and tooth discoloration