Fabkin Hormone As A Marker For Early Diagnosis Of Atherosclerosis And Its Relationship With Some Clinical Biochemical Variables

Abstract

Given that atherosclerosis is a very widespread disease worldwide and often leads to an increase in the number of deaths
worldwide, this has provided an incentive to study its influencing factors with the aim of developing early diagnostic parameters
for treatment and prevention. The study included measuring fabkin hormone (FABP4) concentrations and examining their
effect on patients with atherosclerosis by collecting samples from two groups (the first included patients with atherosclerosis and
the second included apparently healthy individuals who served as a control group). Its relationship with clinical biochemical
variables was also investigated by measuring leptin hormone, in resistin hormone, proprotein convertase subtilisin/kexin type
9, high-sensitivity C-reactive protein (hs-CRP), creatine kinase CK-MB, and hormone-sensitive lipase (HSL). The antioxidant
effect of vitamin E, calcium, and glucose was also measured. In addition, lipid profiles and the atherogenic index (AI) were
measured. The effect of body mass index (BMI) was also studied for both groups, and the study found a significant relationship
between FABP4 and other hormonal and biochemical variables in atherosclerosis. Finally, it was found that FABP4 levels
were higher in patients compared to the control group, which may serve as a biomarker in the early stages of atherosclerosis.