A Study Of The Incidence Of Cystoid Macular Edema In Patients With Psuedoexfoliation Syndrome Following Small Incision Cataract Surgery
DOI:
https://doi.org/10.64252/k4ewk065Keywords:
PXF, CME, blood aqueous barrier.Abstract
Psuedoexfoliation syndrome is an age related disorder caused by fibrillar granular extracellular material which deposits in the anterior segment of the eye and other body tissues. It is associated with open and closed angle glaucoma and cataract. Eyes with PXF were reported to have prolonged aqueous flare following cataract surgery, the fragility of the blood-ocular barrier and intense postoperative inflammation may be responsible for a higher risk of pseudophakic macular edema in PXF eyes.
Aim
To study the incidence of postoperative cystoid macular edema in patients with PXF undergoing routine small incision cataract surgery
Materials & Methods
It was a prospective study conducted at the department of ophthalmology at Sree Balaji Medical college and hospital between January 2024 to December 2024. A total of 50 patients with PXF syndrome with and without glaucoma were included in the study. They underwent unilateral small incision cataract surgery and postoperative assessment with visual acuity, fundus examination and OCT was done at 2 weeks, 4 weeks and 8 weeks respectively.
Results
Four patients showed clinical and OCT evidence of cystoid macular edema at the eighth week follow up and no association was noted with co-existing glaucoma. 40 patients had good visual recovery, 8 patients impaired and 2 patients poor postoperatively.
Discussion
Cystoid macular edema (CME) is the most common cause of visual impairment related to the postoperative period of uncomplicated cataract surgery. CME has a low incidence of 0.1%–2.35% and occurs between the fourth and tenth postoperative week. The extensive blood-aqueous barrier breakdown in eyes with PEX following intraocular surgery is an important risk factor for early or late postoperative complications. The alterations of the blood-aqueous barrier should be considered in the medical and surgical treatment of eyes with PEX.
