Pharm acognostic And Analytical Standardization Of Bacopa Monnieri Linn. And Coccinia Indica W& A - Ayurvedic Medicines For Shayyamutra W.S.R. To Enuresis In Children

Abstract

Introduction: Shayyamutra is an emerging problem now a day. It may lead to psychological burden for family. It can be managed with the help of Ayurvedic drugs. Bacopa monnieri Linn. And Coccinia indica W&A are good choice for the same. Proper identification and standardization of these drug is must for the era of globalization. Aim and objectives: To study the macroscopic and microscopic characters of Brahmi Panchanga and Mool of Bimbi, To study the powder microscopy of both the drugs, To analyze the samples by using different physico-chemical parameters. Material and Method: The identification was carried out based on the morphological features, organoleptic features and powder microscopy of the individual drugs. Loss on drying Ash value, Acid insoluble ash, Water soluble extractive, Alcohol soluble extractive, PH value, Tablet Hardness, Tablet disintegration time and Uniformity (Average Wt.) have been tested at modern pharmaceutical laboratory. Result: Bacopa monnieri Linn powder showed xylem vessels with reticulate thickening, glandular hairs, simple, round and oval starch grains, measuring 4-14 μ in diameter. Coccinia indica W&A powder showed groups of round to polygonal parenchymatous cells, reticulate, spiral and pitted vessels, aseptate fibres, palisade cells, stone cells, simple and compound, round to oval starch grains. Weight variation was found more in Group A tablets i.e. 560 mg average
weight of a single tablet while average weight of Group B tablet was found 480, which were within permissible variation. Conclusion: All the parameters found almost equal to the given standard values for a Brahmi (Bacopa monnieri Linn) and Bimbi (Coccinia indica W& A) except uniformity of Brahmi tablets