Surprise Lesion In A Suspected Cholesteatoma
DOI:
https://doi.org/10.64252/wrcrjv23Keywords:
middle ear adenoma (MEA), middle ear neuroendocrine tumor (MeNETs), neuroendocrine adenoma (NEA), immunohistochemistry (IHC), periodic acid shiff stain (PAS), World health organization (WHO)Abstract
Middle ear adenoma is a rare, benigntumour and accounts for minor proportion ofmiddle ear glandular neoplasms. We report a case of middle ear adenoma in a 39/male came with complaints of right ear discharge on & off for one year. The case was clinically diagnosed as right unsafe ear after imaging study revealed the features of right ear cholesteatoma and the patient was operated on modified radical mastoidectomy. On microscopy, sections showed nonspecific inflammatory granulation tissueandthere werefew glandular proliferations lined by single to stratified layers of cuboidal to columnar epithelium with periodic acid shiff stain positive mucin. The immunohistochemical markers demonstrates positivity for cytokeratin and negativity for chromogranin. With all the Hematoxylin and Eosin, Periodic acid shiff stain and Immunohistochemical markers evaluation, the middle ear adenoma was diagnosed.