Synthesis Of 2-Aminothiazole From Methyl Carbonyl Compound Using Zno Nanoparticles -Chloramine-T Catalytic System

Abstract

Metal oxide nanoparticles have been receiving considerable attention for their potential applications in optoelectronics, nano sensors, nano devices, nano electronics, information storage and catalysis. An efficient protocol is developed for the synthesis of 2-aminothiazole from chloroacetaldehyde using zinc oxide nano particles-chloramine -T reagent catalytic system. The zinc oxide nanoparticles were characterized by using ultraviolet spectroscopy and FT-IR spectroscopic study, EDX and SEM.  In the present study, ZnO/Chloramine-T has been introduced as new, mild, stable and excellent catalytic system for the synthesis of 2-aminothiazole from thiourea, which has an important role in synthetic and medicinal chemistry.