Gingival Plasma Cell Granuloma: An Emerging Incidence Of Rare Pathology - A Case Series And Literature Review

Abstract

Gingival Plasma Cell Granuloma (PCG) is a rare, reactive, benign lesion characterized by the predominance of polyclonal plasma cells. These lesions are often mistaken for pyogenic granuloma and plasma cell neoplasm and require ancillary studies for accurate diagnosis. The case series gives an insight on the 2 cases of PCG and the importance of clinical-histological examination for appropriate diagnosis. The first case is of a female patient who presented with buccal swelling over the right maxillary tooth region, while the second case is of a male patient who presented with bucco-palatal swelling in the left upper back tooth region. Both cases were managed by excisional biopsy and did not report any recurrences. Histological examination of both cases showed parakeratinized epithelium with plasma cell infiltrate in the connective tissue. It is thus essential to differentiate PGC from other potential malignant lesions of the oral cavity to ensure appropriate management.