Antimicrobial Efficacy And Phytochemical Profiling Of Adina Cordifolia Bark Extract: A Gc-Ms And Mic-Based Study

Abstract

This study explores the antimicrobial potential and phytochemical profile of Adina cordifolia bark extracts. Using solvents of varying polarity, the extracts were tested against Gram-positive and Gram-negative bacteria, as well as fungal strains. The methanolic and acetone extracts showed significant activity, particularly against E. coli and C. albicans, with MIC values between 2–8 µg/mL. GC-MS analysis of the methanolic extract identified bioactive compounds such as benzaldehyde derivatives and diphenylsulfones, suggesting their role in antimicrobial efficacy. The results support the ethnomedicinal relevance of A. cordifolia and indicate its potential as a natural antimicrobial source.