Evaluation Of Vitamin D3 And Interleukin 6 In Children With Thyroid Disorders In Thi-Qar Province/ Iraq

Abstract

Objective: The study aims to determine the relationship between thyroid disorders and the concentration of vitamin D3, Interleukin-6, TSH, T3, T4 hormones, Liver enzyme (AST, ALP, and ALT) and kidney functions (Uric acid, Creatinine, and Urea) in blood samples of children in Thi-Qar Province, Iraq.

Methods: The study sample was divided into three groups: the first group (control), the second group (hypothyroidism) and the third group (hyperthyroidism). The above-mentioned criteria were measured for the three groups according to the work methods specified in the detection tools.The study sample consisted of the patients attending Al-Rifai Teaching Hospital and Endocrinology center in Thi-Qar, from August 4, 2024, to June 10, 2025.

Results: The results of this study showed a significant increase in Vit. D3, TSH and IL-6 in the second group. Also, there is a significant increase in Vit. D3, T4, ALT, urea, and uric acid in the third group when compare with the first group and there is a significant decrease in AST and ALP in the second and third groups compare with first group, while a significant decrease in T4 in the second group. 

Conclusion: There is a clear and reciprocal effect between thyroid disorders and vit-D3, IL-6, TSH, T3, T4, Urea, Uric acid, ALT, AST, ALP.