Prevalence of Dry Eye in Patients with Pseudoexfoliation
DOI:
https://doi.org/10.64252/r2vtct05Keywords:
1. DED- Dry Eye Disease 2. PXF/PEX -Pseudoexfoliation 3. TBUT – Tear Film Breakup Time 4. MGD – Meibomian Gland Dysfunction 5. MMP – matrix metalloproteinases 6. IL – Interleukin 7. TNF – Tumor Necrosis Factor 8. IFN – Interferon 9. LFU – Lacrimal functional Unit 10. CGRP – Calcitonin gene related peptide 11. ROS – Reactive Oxygen Species 12. OSDI – Ocular Surface Disease Index 13. MAPK – Mitogen Activated Protein KinaseAbstract
Background: Dry eye disease (DED) is a multifactorial condition of the ocular surface characterized by loss of homeostasis of the tear film, leading to symptoms such as irritation, visual disturbance, and potential damage to the ocular surface. Pseudoexfoliation syndrome has a notable impact on the ocular surface, leading to structural and functional changes.
Aim: To estimate the prevalence of dry eye disease in patients with pseudoexfoliation
Methods: The study included 350 patients with pseudoexfoliation attending ophthalmology OPD, complete evaluation of the patient is done. Specific tests to assess the dry eye is done using Schirmer’s test, tear film break up time (TBUT), and ocular surface fluorescein staining. Prevalence of dry eye is estimated.
Results: 11.14% of the study subjects were diagnosed with dry eye.
Conclusion: This study confirms a strong association between pseudoexfoliation syndrome and dry eye disease.
