A Review On Antimicrobial Activity Of Aloe Barbadensis And Ocimum Gratissimum Against Acne Causing Bacteria

Abstract

Acne vulgaris is a frequent, chronic skin disease that primarily occurs in teenagers and young adults. It arises as the result of a variety of factors, such as overproduction of oil, blocked hair follicles, bacteria—particularly Cutibacterium acnes—and immune system-driven inflammation. Though antibiotics have been utilized to treat acne for many years, they are gradually losing their efficacy as a result of developing resistance and adverse effects. Consequently, there is growing demand for natural and safer treatment alternatives. In this review, two promising medicinal plants—Aloe barbadensis (popularly referred to as Aloe vera) and Ocimum gratissimum (also known as clove basil)—are examined and their potential in the management of acne. Aloe vera has been long recognized for its calming, antibacterial, anti-inflammatory, and healing properties due to its dense composition of natural compounds such as polysaccharides, vitamins, and antioxidants. Clove basil, on the other hand, is loaded with potent compounds such as eugenol and flavonoids that not only combat bacteria, fungi, and inflammation but also contribute to reducing acne symptoms and breakouts when used singly or in combination with other therapies. Nevertheless, there must be additional clinical studies to prove their efficacy as well as to create standardized, dependable products. With increasing interest in natural and environmentally friendly skin care, these botanical alternatives could provide a safe and viable alternative in acne therapy.