Comparative Evaluation Of Axiostat Vs . Gelfoam For Post-Extraction Hemostasis And Healing In Patients On Antiplatelet Therapy: A Clinical Study

Abstract

Objectives: To evaluate the effectiveness of Axiostat Hemostatic Dental (AHD) dressing compared to Gelfoam in achieving hemostasis and promoting healing following mandibular tooth extractions in patients on antiplatelet therapy.

Materials and Methods: A split-mouth study was conducted on 12 patients requiring bilateral mandibular molar extractions. AHD was applied to the Site A (Study group), and Gelfoam was applied to the site B (Control group). Hemostasis time was recorded, and healing was assessed on the 7th, 14th, and 21st day using the Landry, Turnbull, and Howley index.

Results: AHD demonstrated a significantly faster hemostasis time (1 minute 36 seconds) compared to Gelfoam (10 minutes 45 seconds). Enhanced epithelialization and reduced granulation tissue were observed in the AHD group on the 7th day, with consistent superiority in healing outcomes noted on the 21st day.

Conclusion: Axiostat demonstrated superior hemostatic efficacy and healing outcomes compared to Gelfoam, suggesting its potential as a preferred local hemostatic agent in dental extractions for patients on antiplatelet therapy.