Study Of Hormone Disbalance In Females And Its Correlation With Fsh And Tsh Biochemical Markers

Abstract

The maintenance of female reproductive health depends heavily on hormonal balance. By concentrating on two important endocrine indicators, follicle stimulating hormone (FSH) and thyroid stimulating hormone (TSH), this study seeks to examine the relationship between hormonal abnormalities and reproductive dysfunctions. Based on their hormonal profiles and clinical symptoms, including irregular menstruation, infertility, and ovulatory status, 70 female patients, ages 15 to 45, were assessed and divided into normal and abnormal groups. The Enzyme-Linked Immunosorbent Assay (ELISA) was used to measure the levels of hormones. Thirty-five subjects had normal FSH and TSH levels, whereas the other thirty-five had either hyperthyroidism or hypothyroidism. A disturbed pituitary-thyroid-gonadal axis was indicated by high TSH and FSH levels in hypothyroid patients, whereas both hormones were repressed in hyperthyroid patients. Furthermore, aberrant FSH and TSH profiles were seen in a considerable percentage of individuals with anovulation, irregular menstruation, and infertility. The results show a definite hormonal interaction between the gonadal and thyroid axes, with ovarian function and reproductive potential directly impacted by thyroid dysfunction.  In order to provide a more comprehensive approach to female reproductive care, our findings justify the inclusion of hormonal profiling in standard gynaecological examinations.