To Study Of Efficacy Of Malati – Madhuka Gel On Garbhini Kikkisa (Straie Gravidarum)

Abstract

Striae gravidarum (SG), commonly known as stretch marks, affect up to 90% of pregnant women, often causing cosmetic and psychological distress. Ayurveda identifies this condition as Garbhini Kikkisa, a Tridoshaja disorder characterized by kandu (itching), daha (burning), and vaivarnya (discoloration). Despite being medically harmless, Striae gravidarum (impairs quality of life, prompting the need for safe, effective, and economical therapies during pregnancy. To evaluate the clinical efficacy and safety of a gel formulation containing Malati (Jasminum officinale) and Madhuka (Glycyrrhiza glabra) in the management of Garbhini Kikkisa. An open-label, prospective clinical study was conducted on 33 antenatal women between 21–30 years of age in the 2nd or 3rd trimester presenting with Kikkisa. Malati–Madhuka Gel was applied twice daily for 4 weeks. Assessment was made on subjective parameters (kandu, daha, vaivarnya) and objective measures (scar grading, Davey’s scoring for striae distribution). Data were analyzed using the Wilcoxon signed-rank test. The formulation produced complete relief in itching (100%) and burning sensation (100%), along with 60% improvement in discoloration. However, only 22.85% improvement was observed in scar length and depth. The gel was well tolerated, with no adverse events reported. Malati–Madhuka Gel is highly effective in alleviating the symptomatic aspects of Kikkisa, though its impact on structural striae reduction is limited. The formulation is safe, economical, and suitable for use during pregnancy. Larger randomized controlled trials are recommended.