Comparative Efficacy Of Vidangadi Lauha And Orlistat In The Management Of Sthaulya: A Randomized Controlled Clinical Trial

Abstract

Background-  Obesity is a major global health concern, resulting from an imbalance between energy intake and expenditure, which leads to excessive fat accumulation and reduced life expectancy. In Ayurveda, this condition is described as Sthaulya, one of the Ashta Nindita Purusha. With it’s growing prevalence worldwide, the need for effective and sustainable management strategies has become increasingly important.

Aim: To evaluate the efficacy of Vidangadi Lauha in the management of Sthaulya (obesity).

Objectives: To observe the adverse effects of Vidangadi Lauha in Sthaulya.

Methodology: A randomized controlled clinical study was conducted with two groups. The trial group received Vidangadi Lauha 1 g thrice daily, and the control group received Orlistat 60 mg twice daily for a duration of three months.

Results: Both Vidangadi Lauha and Orlistat demonstrated a reduction in weight and BMI. However, Vidangadi Lauha was more effective, showing a significant reduction in body fat, visceral fat, body circumferences, cholesterol, and triglycerides, along with relief in the symptoms of Sthaulya. In the Vidangadi Lauha group, 40% of patients showed marked improvement and 60% showed moderate improvement, whereas Orlistat produced mostly mild improvement.

Conclusion: Both treatments were effective in reducing weight, BMI, body fat, and visceral fat. Vidangadi Lauha was superior to Orlistat in improving body fat percentage, visceral fat, skinfold thickness, body circumferences, lipid profile, and Ayurvedic symptoms of Sthaulya. Vidangadi Lauha also demonstrated better patient compliance and fewer adverse effects, establishing it as a safer and more holistic option for obesity management.