A Preliminary Study Of The Development Of An Innovative Prasadana Anjana [Ophthalmic Collyrium] Containing Triphala Ghrita, Soot and Mukta Pishti

Abstract

Vision is regarded as the most vital sense, and Ayurveda emphasises ocular health under Netra Vyadhi. Prasadana Anjana, recommended for daily use, is described to enhance vision and prevent disorders. This study was aimed to develop and analyse an innovative Prasadana Anjana containing Mukta Pishti (pishti of pearls) and Triphala Ghṛita as a safe Ayurvedic ophthalmic formulation. Mukta (pearls) were purified with Jayanti (Sesbania sesban) Swarasa and converted to Pishti through 21 bhavana cycles with rose water, followed by analysis by PSA, XRD, FTIR, and Raman spectroscopy. Triphala Ghṛita was prepared as per classical guidelines and tested by HPTLC. Carbon soot was prepared using purified cow’s ghṛita and analyzed by FTIR and Raman spectroscopy. The final formulation was prepared with Mukta Pishti, Triphala Ghṛita, Bhimseni Camphor, beeswax, coconut oil, and carbon soot using the double-boiling method and stored aseptically. Mukta Pishti attained nanoscale fineness (80–300 nm). XRD confirmed retention of the aragonite phase; FTIR and Raman validated carbonate and protein structures. HPTLC confirmed gallic acid in Triphala Ghṛita. The final formulation was smooth, homogeneous, stable for three months, and free from harmful additives. The innovative Prasadana Anjana proved safe, stable, and therapeutically relevant, offering a validated Ayurvedic alternative to commercial kajals often contaminated with lead and parabens.