Rice Husk-Derived Cellulose Nanofiber Mats: Next-Generation Wound Dressing Materials With Antibiofilm Properties

Abstract

This study offers a sustainable method for creating useful cellulose nanofibrous mats with strong antibiofilm qualities from rice husk, a plentiful agricultural byproduct. To create two different mats (Mat 1 and Mat 2), cellulose that was taken out of rice husk was combined with polymers and electrospun. Both mats had randomly ordered, uniformly distributed, defect-free fibers, as shown by scanning electron microscopy. Staphylococcus aureus and Pseudomonas aeruginosa, two opportunistic organisms, were used to investigate their antibacterial and antibiofilm properties. While Mat 1 had no antibiofilm effect and commercial cellulose showed little action, Mat 2 showed notable antibiofilm efficacy, lowering the production of S. aureus biofilm by roughly 58% and P. aeruginosa biofilm by 68%. These results highlight rice husk's potential as a renewable feedstock for cutting-edge biomaterials and open the door for environmentally friendly, next-generation materials in wound care and biomedical device applications that target illnesses resistant to antibiotics.