Phyto-Therapeutic Potential Of Flower Of The Wonder Tree, Prosopis Cineraria In Complete Freund’s Adjuvant Model: An Anti-Arthritis Study

Abstract

Numerous distinguished researchers have thoroughly investigated Prosopis cineraria's therapeutic potential against a range of major illnesses, although its efficacy against CFA (Complete freund’s adjuvant. Consequently, the current experimental study was carried out to identify and evaluate the anti-inflammatory  capacity of Prosopis cineraria ethanol extract to prevent inflammation caused by CFA in Wistar albino rats. This research aimed to evaluate the effect of ethanol extract flower of prosopis cineraria on parameter limb circumfarence, change body weight, paw volume and hematology profile in rats induced by complete freund’s adjuvant. Thirty rats were divided into five groups each group contain 6 rats. Ethanol extract flower of prosopis cineraria doses selected of 250 mg/kg and 500 mg/kg orally. Each group was given the test preparation orally for 21 days. After 1 h, CFA induced at a dose 10 mg/mL hind paw of animal under mild anesthesia with diethyl ether. On the 21th day, to measure all the parametersand blood samples were collected. Finding was shows ethanol extract flower of prosopis cineraria at a dose of 500 mg/kg orally good effect of limb circumference, body weight, paw volume and haematological parameters as compare with normal group (p>0.05)..