Evaluation Of Hematological Parameters Of Early Osteoporosis In Patients With Celiac Disease In Wasit Governorate

Abstract

The aim of this study was to evaluate some hematological parameters in early osteoporosis in  patients with celiac disease (CD).  in the past decades, the incidence of osteoporosis associated with celiac disease  has increased at an alarming rate among the elderly and postmenopausal women. This disease affects the effectiveness of many hormones, vitamins, and nutrients in the body and is characterized by deterioration of bone mass and microarchitecture, including the risk of eventual fractures. The  study was conducted in the gastrointestinal  unit and the prosthetics unit of Al-Zahraa Teaching Hospital, and the immunology unit and joints unit of  Al-Karama Teaching Hospital in Wasit Governorate. During the period from October 2024 to February 2025.This study aimed to examination of risk factors (height, weight, age, sex, inheritance of the disease in the family, medical history, symptoms of the disease, other diseases, treatment methods). For the purpose of studying the hematological parameters of osteoporosis in patients celiac disease and comparing those results. This study was done on (75)  blood samples were collected from elderly men and women Iraqi, including (25) blood samples from the group of patients with osteoporosis    associated with celiac disease. (13) blood samples from females, (12) blood samples from male, and (50) blood sample from the control group. These samples were divided into two age groups, with (55-65) years represents the first age group, and (65-75) years represents the second age group. Samples were collected based on the incidence of osteoporosis in patients with CD and type of treatment, as well as the diagnosis of all patients according to international standard by the physician. The results of our study regarding diagnostic of early osteoporosis with celiac disease showed a significant decrease in parameters (ESR, Hb ,PCV , Lymphocyte , Basophil , Eosinophil , Neutrophil) and a significant increase in (WBC , RBC ,  Monocyte )in affected individuals with a p < 0.05. A non-significant increase of gender- linked in ( WBC , RBC ,ESR , PCV , Hb, Monocyte ,  Lymphocyte , Basophil , Eosinophil , Neutrophil )  in infected people When p ≥ 0.05. Conclusions: In blood early osteoporosis in patients with  celiac diseases on blood parameters, values showed A significant decrease  in parameters  and a corresponding increase in other parameters  compared to healthy people at the level of p ≥ 0.05  , which is clear evidence of the presence of infections and anemia.